African Program for Onchocerciasis Control 1995–2010: Impact of Annual Ivermectin Mass Treatment on Off-Target Infectious Diseases
Identifieur interne : 002171 ( Main/Exploration ); précédent : 002170; suivant : 002172African Program for Onchocerciasis Control 1995–2010: Impact of Annual Ivermectin Mass Treatment on Off-Target Infectious Diseases
Auteurs : Stanimira P. Krotneva [Pays-Bas] ; Luc E. Coffeng [Pays-Bas] ; Mounkaila Noma [Burkina Faso] ; Honorat G. M. Zouré [Burkina Faso] ; Lalle Bakoné [Burkina Faso] ; Uche V. Amazigo [Nigeria] ; Sake J. De Vlas [Pays-Bas] ; Wilma A. Stolk [Pays-Bas]Source :
- PLoS Neglected Tropical Diseases [ 1935-2727 ] ; 2015.
Abstract
Since its initiation in 1995, the African Program for Onchocerciasis Control (APOC) has had a substantial impact on the prevalence and burden of onchocerciasis through annual ivermectin mass treatment. Ivermectin is a broad-spectrum anti-parasitic agent that also has an impact on other co-endemic parasitic infections. In this study, we roughly assessed the additional impact of APOC activities on the burden of the most important off-target infections: soil-transmitted helminthiases (STH; ascariasis, trichuriasis, hookworm, and strongyloidiasis), lymphatic filariasis (LF), and scabies. Based on a literature review, we formulated assumptions about the impact of ivermectin treatment on the disease burden of these off-target infections. Using data on the number of ivermectin treatments in APOC regions and the latest estimates of the burden of disease, we then calculated the impact of APOC activities on off-target infections in terms of disability-adjusted life years (DALYs) averted. We conservatively estimated that between 1995 and 2010, annual ivermectin mass treatment has cumulatively averted about 500 thousand DALYs from co-endemic STH infections, LF, and scabies. This impact comprised approximately an additional 5.5% relative to the total burden averted from onchocerciasis (8.9 million DALYs) and indicates that the overall cost-effectiveness of APOC is even higher than previously reported.
Url:
DOI: 10.1371/journal.pntd.0004051
PubMed: 26401658
PubMed Central: 4581698
Affiliations:
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Stolk</name><affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands</addr-line></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author></analytic><series><title level="j">PLoS Neglected Tropical Diseases</title><idno type="ISSN">1935-2727</idno><idno type="eISSN">1935-2735</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Since its initiation in 1995, the African Program for Onchocerciasis Control (APOC) has had a substantial impact on the prevalence and burden of onchocerciasis through annual ivermectin mass treatment. Ivermectin is a broad-spectrum anti-parasitic agent that also has an impact on other co-endemic parasitic infections. In this study, we roughly assessed the additional impact of APOC activities on the burden of the most important off-target infections: soil-transmitted helminthiases (STH; ascariasis, trichuriasis, hookworm, and strongyloidiasis), lymphatic filariasis (LF), and scabies. Based on a literature review, we formulated assumptions about the impact of ivermectin treatment on the disease burden of these off-target infections. Using data on the number of ivermectin treatments in APOC regions and the latest estimates of the burden of disease, we then calculated the impact of APOC activities on off-target infections in terms of disability-adjusted life years (DALYs) averted. We conservatively estimated that between 1995 and 2010, annual ivermectin mass treatment has cumulatively averted about 500 thousand DALYs from co-endemic STH infections, LF, and scabies. This impact comprised approximately an additional 5.5% relative to the total burden averted from onchocerciasis (8.9 million DALYs) and indicates that the overall cost-effectiveness of APOC is even higher than previously reported.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Amazigo, U" uniqKey="Amazigo U">U Amazigo</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Coffeng, Le" uniqKey="Coffeng L">LE Coffeng</name></author><author><name sortKey="Stolk, Wa" uniqKey="Stolk W">WA Stolk</name></author><author><name sortKey="Zoure, Hgm" uniqKey="Zoure H">HGM Zouré</name></author><author><name sortKey="Veerman, Jl" uniqKey="Veerman J">JL Veerman</name></author><author><name sortKey="Agblewonu, Kb" uniqKey="Agblewonu K">KB Agblewonu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Coffeng, Le" uniqKey="Coffeng L">LE Coffeng</name></author><author><name sortKey="Stolk, Wa" uniqKey="Stolk W">WA Stolk</name></author><author><name sortKey="Zoure, Hgm" uniqKey="Zoure H">HGM Zouré</name></author><author><name sortKey="Veerman, Jl" uniqKey="Veerman J">JL Veerman</name></author><author><name sortKey="Agblewonu, Kb" uniqKey="Agblewonu K">KB Agblewonu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Campbell, Wc" uniqKey="Campbell W">WC Campbell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dourmishev, Al" uniqKey="Dourmishev A">AL Dourmishev</name></author><author><name sortKey="Dourmishev, La" uniqKey="Dourmishev L">LA Dourmishev</name></author><author><name sortKey="Schwartz, Ra" uniqKey="Schwartz R">RA Schwartz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bethony, J" uniqKey="Bethony J">J Bethony</name></author><author><name sortKey="Brooker, S" uniqKey="Brooker S">S Brooker</name></author><author><name sortKey="Albonico, M" uniqKey="Albonico M">M Albonico</name></author><author><name sortKey="Geiger, Sm" uniqKey="Geiger S">SM Geiger</name></author><author><name sortKey="Loukas, A" uniqKey="Loukas A">A Loukas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ottesen, Ea" uniqKey="Ottesen E">EA Ottesen</name></author><author><name sortKey="Hooper, Pj" uniqKey="Hooper P">PJ Hooper</name></author><author><name sortKey="Bradley, M" uniqKey="Bradley M">M Bradley</name></author><author><name sortKey="Biswas, G" uniqKey="Biswas G">G Biswas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Feldmeier, H" uniqKey="Feldmeier H">H Feldmeier</name></author><author><name sortKey="Heukelbach, J" uniqKey="Heukelbach J">J Heukelbach</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hotez, Pj" uniqKey="Hotez P">PJ Hotez</name></author><author><name sortKey="Kamath, A" uniqKey="Kamath A">A Kamath</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brooker, S" uniqKey="Brooker S">S Brooker</name></author><author><name sortKey="Hotez, Pj" uniqKey="Hotez P">PJ Hotez</name></author><author><name sortKey="Bundy, Dap" uniqKey="Bundy D">DAP Bundy</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Slater, H" uniqKey="Slater H">H Slater</name></author><author><name sortKey="Michael, E" uniqKey="Michael E">E Michael</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Murray, Cjl" uniqKey="Murray C">CJL Murray</name></author><author><name sortKey="Vos, T" uniqKey="Vos T">T Vos</name></author><author><name sortKey="Lozano, R" uniqKey="Lozano R">R Lozano</name></author><author><name sortKey="Naghavi, M" uniqKey="Naghavi M">M Naghavi</name></author><author><name sortKey="Flaxman, Ad" uniqKey="Flaxman A">AD Flaxman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hotez, Pj" uniqKey="Hotez P">PJ Hotez</name></author><author><name sortKey="Alvarado, M" uniqKey="Alvarado M">M Alvarado</name></author><author><name sortKey="Basa Ez, M G" uniqKey="Basa Ez M">M-G Basáñez</name></author><author><name sortKey="Bolliger, I" uniqKey="Bolliger I">I Bolliger</name></author><author><name sortKey="Bourne, R" uniqKey="Bourne R">R Bourne</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Taticheff, S" uniqKey="Taticheff S">S Taticheff</name></author><author><name sortKey="Kebede, A" uniqKey="Kebede A">A Kebede</name></author><author><name sortKey="Bulto, T" uniqKey="Bulto T">T Bulto</name></author><author><name sortKey="Werkeneh, W" uniqKey="Werkeneh W">W Werkeneh</name></author><author><name sortKey="Tilahun, D" uniqKey="Tilahun D">D Tilahun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tielsch, Jm" uniqKey="Tielsch J">JM Tielsch</name></author><author><name sortKey="Beeche, A" uniqKey="Beeche A">A Beeche</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Anosike, Jc" uniqKey="Anosike J">JC Anosike</name></author><author><name sortKey="Dozie, Ins" uniqKey="Dozie I">INS Dozie</name></author><author><name sortKey="Ameh, Gi" uniqKey="Ameh G">GI Ameh</name></author><author><name sortKey="Ukaga, Cn" uniqKey="Ukaga C">CN Ukaga</name></author><author><name sortKey="Nwoke, Beb" uniqKey="Nwoke B">BEB Nwoke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gutman, J" uniqKey="Gutman J">J Gutman</name></author><author><name sortKey="Emukah, E" uniqKey="Emukah E">E Emukah</name></author><author><name sortKey="Okpala, N" uniqKey="Okpala N">N Okpala</name></author><author><name sortKey="Okoro, C" uniqKey="Okoro C">C Okoro</name></author><author><name sortKey="Obasi, A" uniqKey="Obasi A">A Obasi</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Yelifari, L" uniqKey="Yelifari L">L Yelifari</name></author><author><name sortKey="Bloch, P" uniqKey="Bloch P">P Bloch</name></author><author><name sortKey="Magnussen, P" uniqKey="Magnussen P">P Magnussen</name></author><author><name sortKey="Van Lieshout, L" uniqKey="Van Lieshout L">L van Lieshout</name></author><author><name sortKey="Dery, G" uniqKey="Dery G">G Dery</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Medley, Gf" uniqKey="Medley G">GF Medley</name></author><author><name sortKey="Guyatt, Hl" uniqKey="Guyatt H">HL Guyatt</name></author><author><name sortKey="Bundy, Da" uniqKey="Bundy D">DA Bundy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chan, Ms" uniqKey="Chan M">MS Chan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bundy, Da" uniqKey="Bundy D">DA Bundy</name></author><author><name sortKey="De Silva, Nr" uniqKey="De Silva N">NR de Silva</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Noma, M" uniqKey="Noma M">M Noma</name></author><author><name sortKey="Nwoke, Beb" uniqKey="Nwoke B">BEB Nwoke</name></author><author><name sortKey="Nutall, I" uniqKey="Nutall I">I Nutall</name></author><author><name sortKey="Tambala, Pa" uniqKey="Tambala P">PA Tambala</name></author><author><name sortKey="Enyong, P" uniqKey="Enyong P">P Enyong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brooker, S" uniqKey="Brooker S">S Brooker</name></author><author><name sortKey="Hotez, Pj" uniqKey="Hotez P">PJ Hotez</name></author><author><name sortKey="Bundy, Dap" uniqKey="Bundy D">DAP Bundy</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Belizario, Vy" uniqKey="Belizario V">VY Belizario</name></author><author><name sortKey="Amarillo, Me" uniqKey="Amarillo M">ME Amarillo</name></author><author><name sortKey="De Leon, Wu" uniqKey="De Leon W">WU de Leon</name></author><author><name sortKey="De Los Reyes, Ae" uniqKey="De Los Reyes A">AE de los Reyes</name></author><author><name sortKey="Bugayong, Mg" uniqKey="Bugayong M">MG Bugayong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Freedman, Do" uniqKey="Freedman D">DO Freedman</name></author><author><name sortKey="Zierdt, Ws" uniqKey="Zierdt W">WS Zierdt</name></author><author><name sortKey="Lujan, A" uniqKey="Lujan A">A Lujan</name></author><author><name sortKey="Nutman, Tb" uniqKey="Nutman T">TB Nutman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Naquira, C" uniqKey="Naquira C">C Naquira</name></author><author><name sortKey="Jimenez, G" uniqKey="Jimenez G">G Jimenez</name></author><author><name sortKey="Guerra, Jg" uniqKey="Guerra J">JG Guerra</name></author><author><name sortKey="Bernal, R" uniqKey="Bernal R">R Bernal</name></author><author><name sortKey="Nalin, Dr" uniqKey="Nalin D">DR Nalin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wen, L Y" uniqKey="Wen L">L-Y Wen</name></author><author><name sortKey="Yan, X L" uniqKey="Yan X">X-L Yan</name></author><author><name sortKey="Sun, F H" uniqKey="Sun F">F-H Sun</name></author><author><name sortKey="Fang, Y Y" uniqKey="Fang Y">Y-Y Fang</name></author><author><name sortKey="Yang, M J" uniqKey="Yang M">M-J Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Richard Lenoble, D" uniqKey="Richard Lenoble D">D Richard-Lenoble</name></author><author><name sortKey="Kombila, M" uniqKey="Kombila M">M Kombila</name></author><author><name sortKey="Rupp, Ea" uniqKey="Rupp E">EA Rupp</name></author><author><name sortKey="Pappayliou, Es" uniqKey="Pappayliou E">ES Pappayliou</name></author><author><name sortKey="Gaxotte, P" uniqKey="Gaxotte P">P Gaxotte</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hotez, Pj" uniqKey="Hotez P">PJ Hotez</name></author><author><name sortKey="Molyneux, Dh" uniqKey="Molyneux D">DH Molyneux</name></author><author><name sortKey="Fenwick, A" uniqKey="Fenwick A">A Fenwick</name></author><author><name sortKey="Kumaresan, J" uniqKey="Kumaresan J">J Kumaresan</name></author><author><name sortKey="Sachs, Se" uniqKey="Sachs S">SE Sachs</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Silva, Nr" uniqKey="De Silva N">NR De Silva</name></author><author><name sortKey="Guyatt, Hl" uniqKey="Guyatt H">HL Guyatt</name></author><author><name sortKey="Bundy, Da" uniqKey="Bundy D">DA Bundy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Albonico, M" uniqKey="Albonico M">M Albonico</name></author><author><name sortKey="Allen, H" uniqKey="Allen H">H Allen</name></author><author><name sortKey="Chitsulo, L" uniqKey="Chitsulo L">L Chitsulo</name></author><author><name sortKey="Engels, D" uniqKey="Engels D">D Engels</name></author><author><name sortKey="Gabrielli, A F" uniqKey="Gabrielli A">A-F Gabrielli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Moncayo, Al" uniqKey="Moncayo A">AL Moncayo</name></author><author><name sortKey="Vaca, M" uniqKey="Vaca M">M Vaca</name></author><author><name sortKey="Amorim, L" uniqKey="Amorim L">L Amorim</name></author><author><name sortKey="Rodriguez, A" uniqKey="Rodriguez A">A Rodriguez</name></author><author><name sortKey="Erazo, S" uniqKey="Erazo S">S Erazo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Whitworth, Ja" uniqKey="Whitworth J">JA Whitworth</name></author><author><name sortKey="Morgan, D" uniqKey="Morgan D">D Morgan</name></author><author><name sortKey="Maude, Gh" uniqKey="Maude G">GH Maude</name></author><author><name sortKey="Mcnicholas, Am" uniqKey="Mcnicholas A">AM McNicholas</name></author><author><name sortKey="Taylor, Dw" uniqKey="Taylor D">DW Taylor</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Elkins, Db" uniqKey="Elkins D">DB Elkins</name></author><author><name sortKey="Haswell Elkins, M" uniqKey="Haswell Elkins M">M Haswell-Elkins</name></author><author><name sortKey="Anderson, Rm" uniqKey="Anderson R">RM Anderson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xia, Zh" uniqKey="Xia Z">ZH Xia</name></author><author><name sortKey="Su, Yl" uniqKey="Su Y">YL Su</name></author><author><name sortKey="Yao, Sy" uniqKey="Yao S">SY Yao</name></author><author><name sortKey="Shen, Br" uniqKey="Shen B">BR Shen</name></author><author><name sortKey="Wen, Ly" uniqKey="Wen L">LY Wen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shikiya, K" uniqKey="Shikiya K">K Shikiya</name></author><author><name sortKey="Uehara, T" uniqKey="Uehara T">T Uehara</name></author><author><name sortKey="Uechi, H" uniqKey="Uechi H">H Uechi</name></author><author><name sortKey="Ohshiro, J" uniqKey="Ohshiro J">J Ohshiro</name></author><author><name sortKey="Arakaki, T" uniqKey="Arakaki T">T Arakaki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shikiya, K" uniqKey="Shikiya K">K Shikiya</name></author><author><name sortKey="Kinjo, N" uniqKey="Kinjo N">N Kinjo</name></author><author><name sortKey="Uehara, T" uniqKey="Uehara T">T Uehara</name></author><author><name sortKey="Uechi, H" uniqKey="Uechi H">H Uechi</name></author><author><name sortKey="Ohshiro, J" uniqKey="Ohshiro J">J Ohshiro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Datry, A" uniqKey="Datry A">A Datry</name></author><author><name sortKey="Hilmarsdottir, I" uniqKey="Hilmarsdottir I">I Hilmarsdottir</name></author><author><name sortKey="Mayorga Sagastume, R" uniqKey="Mayorga Sagastume R">R Mayorga-Sagastume</name></author><author><name sortKey="Lyagoubi, M" uniqKey="Lyagoubi M">M Lyagoubi</name></author><author><name sortKey="Gaxotte, P" uniqKey="Gaxotte P">P Gaxotte</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Marti, H" uniqKey="Marti H">H Marti</name></author><author><name sortKey="Haji, Hj" uniqKey="Haji H">HJ Haji</name></author><author><name sortKey="Savioli, L" uniqKey="Savioli L">L Savioli</name></author><author><name sortKey="Chwaya, Hm" uniqKey="Chwaya H">HM Chwaya</name></author><author><name sortKey="Mgeni, Af" uniqKey="Mgeni A">AF Mgeni</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nontasut, P" uniqKey="Nontasut P">P Nontasut</name></author><author><name sortKey="Muennoo, C" uniqKey="Muennoo C">C Muennoo</name></author><author><name sortKey="Sa Nguankiat, S" uniqKey="Sa Nguankiat S">S Sa-nguankiat</name></author><author><name sortKey="Fongsri, S" uniqKey="Fongsri S">S Fongsri</name></author><author><name sortKey="Vichit, A" uniqKey="Vichit A">A Vichit</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Olsen, A" uniqKey="Olsen A">A Olsen</name></author><author><name sortKey="Van Lieshout, L" uniqKey="Van Lieshout L">L van Lieshout</name></author><author><name sortKey="Marti, H" uniqKey="Marti H">H Marti</name></author><author><name sortKey="Polderman, T" uniqKey="Polderman T">T Polderman</name></author><author><name sortKey="Polman, K" uniqKey="Polman K">K Polman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Santiago, M" uniqKey="Santiago M">M Santiago</name></author><author><name sortKey="Leitao, B" uniqKey="Leitao B">B Leitão</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stern, Ms" uniqKey="Stern M">MS Stern</name></author><author><name sortKey="Joshpe, G" uniqKey="Joshpe G">G Joshpe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Plaisier, Ap" uniqKey="Plaisier A">AP Plaisier</name></author><author><name sortKey="Cao, Wc" uniqKey="Cao W">WC Cao</name></author><author><name sortKey="Van Oortmarssen, Gj" uniqKey="Van Oortmarssen G">GJ van Oortmarssen</name></author><author><name sortKey="Habbema, Jd" uniqKey="Habbema J">JD Habbema</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dunyo, Sk" uniqKey="Dunyo S">SK Dunyo</name></author><author><name sortKey="Nkrumah, Fk" uniqKey="Nkrumah F">FK Nkrumah</name></author><author><name sortKey="Simonsen, Pe" uniqKey="Simonsen P">PE Simonsen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Taylor, Mj" uniqKey="Taylor M">MJ Taylor</name></author><author><name sortKey="Hoerauf, A" uniqKey="Hoerauf A">A Hoerauf</name></author><author><name sortKey="Bockarie, M" uniqKey="Bockarie M">M Bockarie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Richards, Fo" uniqKey="Richards F">FO Richards</name></author><author><name sortKey="Eigege, A" uniqKey="Eigege A">A Eigege</name></author><author><name sortKey="Pam, D" uniqKey="Pam D">D Pam</name></author><author><name sortKey="Kal, A" uniqKey="Kal A">A Kal</name></author><author><name sortKey="Lenhart, A" uniqKey="Lenhart A">A Lenhart</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kar, Sk" uniqKey="Kar S">SK Kar</name></author><author><name sortKey="Mania, J" uniqKey="Mania J">J Mania</name></author><author><name sortKey="Patnaik, S" uniqKey="Patnaik S">S Patnaik</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Usha, V" uniqKey="Usha V">V Usha</name></author><author><name sortKey="Gopalakrishnan, Nair T V" uniqKey="Gopalakrishnan N">Nair T V Gopalakrishnan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sule, Hm" uniqKey="Sule H">HM Sule</name></author><author><name sortKey="Thacher, Td" uniqKey="Thacher T">TD Thacher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meinking, Tl" uniqKey="Meinking T">TL Meinking</name></author><author><name sortKey="Taplin, D" uniqKey="Taplin D">D Taplin</name></author><author><name sortKey="Hermida, Jl" uniqKey="Hermida J">JL Hermida</name></author><author><name sortKey="Pardo, R" uniqKey="Pardo R">R Pardo</name></author><author><name sortKey="Kerdel, Fa" uniqKey="Kerdel F">FA Kerdel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Heukelbach, J" uniqKey="Heukelbach J">J Heukelbach</name></author><author><name sortKey="Winter, B" uniqKey="Winter B">B Winter</name></author><author><name sortKey="Wilcke, T" uniqKey="Wilcke T">T Wilcke</name></author><author><name sortKey="Muehlen, M" uniqKey="Muehlen M">M Muehlen</name></author><author><name sortKey="Albrecht, S" uniqKey="Albrecht S">S Albrecht</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abedin, S" uniqKey="Abedin S">S Abedin</name></author><author><name sortKey="Narang, M" uniqKey="Narang M">M Narang</name></author><author><name sortKey="Gandhi, V" uniqKey="Gandhi V">V Gandhi</name></author><author><name sortKey="Narang, S" uniqKey="Narang S">S Narang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Badiaga, S" uniqKey="Badiaga S">S Badiaga</name></author><author><name sortKey="Foucault, C" uniqKey="Foucault C">C Foucault</name></author><author><name sortKey="Rogier, C" uniqKey="Rogier C">C Rogier</name></author><author><name sortKey="Doudier, B" uniqKey="Doudier B">B Doudier</name></author><author><name sortKey="Rovery, C" uniqKey="Rovery C">C Rovery</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hengge, Ur" uniqKey="Hengge U">UR Hengge</name></author><author><name sortKey="Currie, Bj" uniqKey="Currie B">BJ Currie</name></author><author><name sortKey="J Ger, G" uniqKey="J Ger G">G Jäger</name></author><author><name sortKey="Lupi, O" uniqKey="Lupi O">O Lupi</name></author><author><name sortKey="Schwartz, Ra" uniqKey="Schwartz R">RA Schwartz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gilmore, Sj" uniqKey="Gilmore S">SJ Gilmore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lawrence, G" uniqKey="Lawrence G">G Lawrence</name></author><author><name sortKey="Leafasia, J" uniqKey="Leafasia J">J Leafasia</name></author><author><name sortKey="Sheridan, J" uniqKey="Sheridan J">J Sheridan</name></author><author><name sortKey="Hills, S" uniqKey="Hills S">S Hills</name></author><author><name sortKey="Wate, J" uniqKey="Wate J">J Wate</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Feldmeier, H" uniqKey="Feldmeier H">H Feldmeier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cestari, Tf" uniqKey="Cestari T">TF Cestari</name></author><author><name sortKey="Pessato, S" uniqKey="Pessato S">S Pessato</name></author><author><name sortKey="Ramos E Silva, M" uniqKey="Ramos E Silva M">M Ramos-e-Silva</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chaccour, Cj" uniqKey="Chaccour C">CJ Chaccour</name></author><author><name sortKey="Kobylinski, Kc" uniqKey="Kobylinski K">KC Kobylinski</name></author><author><name sortKey="Bassat, Q" uniqKey="Bassat Q">Q Bassat</name></author><author><name sortKey="Bousema, T" uniqKey="Bousema T">T Bousema</name></author><author><name sortKey="Drakeley, C" uniqKey="Drakeley C">C Drakeley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boussinesq, M" uniqKey="Boussinesq M">M Boussinesq</name></author><author><name sortKey="Gardon, J" uniqKey="Gardon J">J Gardon</name></author><author><name sortKey="Gardon Wendel, N" uniqKey="Gardon Wendel N">N Gardon-Wendel</name></author><author><name sortKey="Chippaux, J P" uniqKey="Chippaux J">J-P Chippaux</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boussinesq, M" uniqKey="Boussinesq M">M Boussinesq</name></author><author><name sortKey="Kamgno, J" uniqKey="Kamgno J">J Kamgno</name></author><author><name sortKey="Pion, Sd" uniqKey="Pion S">SD Pion</name></author><author><name sortKey="Gardon, J" uniqKey="Gardon J">J Gardon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zoure, Hgm" uniqKey="Zoure H">HGM Zouré</name></author><author><name sortKey="Wanji, S" uniqKey="Wanji S">S Wanji</name></author><author><name sortKey="Noma, M" uniqKey="Noma M">M Noma</name></author><author><name sortKey="Amazigo, Uv" uniqKey="Amazigo 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Khamis</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Burkina Faso</li><li>Nigeria</li><li>Pays-Bas</li></country><region><li>Hollande-Méridionale</li></region><settlement><li>Rotterdam</li></settlement></list><tree><country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Krotneva, Stanimira P" sort="Krotneva, Stanimira P" uniqKey="Krotneva S" first="Stanimira P." last="Krotneva">Stanimira P. Krotneva</name></region><name sortKey="Coffeng, Luc E" sort="Coffeng, Luc E" uniqKey="Coffeng L" first="Luc E." last="Coffeng">Luc E. Coffeng</name><name sortKey="De Vlas, Sake J" sort="De Vlas, Sake J" uniqKey="De Vlas S" first="Sake J." last="De Vlas">Sake J. De Vlas</name><name sortKey="Stolk, Wilma A" sort="Stolk, Wilma A" uniqKey="Stolk W" first="Wilma A." last="Stolk">Wilma A. Stolk</name></country><country name="Burkina Faso"><noRegion><name sortKey="Noma, Mounkaila" sort="Noma, Mounkaila" uniqKey="Noma M" first="Mounkaila" last="Noma">Mounkaila Noma</name></noRegion><name sortKey="Bakone, Lalle" sort="Bakone, Lalle" uniqKey="Bakone L" first="Lalle" last="Bakoné">Lalle Bakoné</name><name sortKey="Zoure, Honorat G M" sort="Zoure, Honorat G M" uniqKey="Zoure H" first="Honorat G. M." last="Zouré">Honorat G. M. Zouré</name></country><country name="Nigeria"><noRegion><name sortKey="Amazigo, Uche V" sort="Amazigo, Uche V" uniqKey="Amazigo U" first="Uche V." last="Amazigo">Uche V. 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